Human Evolutionary and Population Genomics
We are interested in molecular evolution and its implications in human population history and medical genomics. We aim to integrate evolutionary theory, genomics and personalized medicine in different projects involving large collections of populations, primarily from the Americas and the Pacific.
Our current work involves the use of genome-wide data sets to study fine-scale patterns of population structure in both Native Americans and Hispanic/Latino populations from throughout the Americas. One of the major goals is to better understand the evolutionary processes, including natural selection, that have shaped Native American genomes during the last ~10,000 years of independent evolution since the peopling of the Americas and before the European contact.
Another major goal is aimed at understanding the dynamics of the admixture process in present day Hispanic/Latino populations since the European contact. By applying methods of local ancestry estimation we are trying to trace back ancestry-specific segments of the genome to their potential source populations at the subcontinental level. Defining patterns of local variation and subcontinental ancestry in admixed populations and individual genomes is also allowing the field to move towards a more personalized view of medical genomics and to promote the study of diverse populations underrepresented in current catalogs of human variation.
PhD and Postdoc positions are currently available! Candidates with a strong background in bioinformatics, large-scale genomics and/or statistical genetics are encouraged to apply. If you are interested in joining the lab please send a copy of your CV and brief statement of your interests to: email@example.com
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